I use Sufix 832 braid with a P-Line fluorocarbon leader. I use the biggest braid I can get which helps with the digging, I fill my spool with cheap mono and only use about 75 yards of braid which also helps. Hook sets with a braid/fluoro are hands down the best. I use the alberto knot to join my braid to other lines and to my knowledge I've never lost a fish due to knot failure! This is typically how I set up my flipping/pitching combos.
For everything else I use Sufix Elite Mono, best line ever IMO!!